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Novartis Oral BTK Inhibitor Remibrutinib Cuts Relapse Rate in Phase III MS Trials

Published: Updated: By 24TopNews Editorial Desk

Novartis announced on September 2, 2026, positive topline results from the Phase III REMODEL-1/-2 trials evaluating remibrutinib in relapsing multiple sclerosis. Remibrutinib is an oral Bruton's tyrosine kinase inhibitor.

In two Phase III trials involving adult patients with relapsing multiple sclerosis, remibrutinib demonstrated superiority over teriflunomide in reducing the annualized relapse rate and inflammatory brain lesions, while maintaining a favorable safety profile.

24TOPNEWS IMPACT INTELLIGENCE

Why this event matters

The event has a measured impact on 1 industry. The strongest current signal is positive for Pharmaceuticals, with intensity 50/100 and 80% confidence over a short term horizon.

Healthcare · 13.1

Pharmaceuticals

Direction
positive
Intensity
50
Confidence
80%
Horizon
Short term
Effective impact +24

Impact figures are analytical estimates that combine direction, intensity, confidence and event importance. They are not investment advice.